Issue 141

Neuroimaging study measures brain activity under psychedelic medicines

Kernel has published results from its Cybin-sponsored neuroimaging study which show the ability of Kernel’s Flow1 system to capture and analyse brain changes induced by psychedelics.

To date, real-time quantification of brain activity during the psychedelic experience has been a major barrier to psychedelics research. Many studies rely on subjective self-reporting, and fMRI machines can pose challenges due to high running costs and the experience for the participant of being in an fMRI whilst under the influence of a psychedelic is not ideal.

However, Kernel’s Flow1 device enables this real-time data collection of brain activity during the experience thanks to the use of near-infrared spectroscopy, providing measurements of blood oxygenation changes in the brain associated with neural activity.

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AWAKN COMPLETES SALE OF AWAKN CLINICS IN NORWAY

This marks Awakn’s exit from healthcare services and enables the company to focus solely on drug development.

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NAVIGATING THE PSYCHEDELIC INDUSTRY SHAKEOUT

The market downturn has largely mirrored that of the broader biotech sector, with investors pivoting away from risky assets.

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BUSINESS AND INVESTMENT

MPM BioImpact completes acquisition of Reunion Neuroscience. The all-cash transaction was valued at approximately US$13.1 million.

Eating disorders are on the rise in UK children. Services are struggling to keep pace with demand.

Cybin announces pricing of public offering. The company hopes to raise US$8.25 million for drug development.

Accessing psilocybin in the UK. The psychedelic medicine is difficult to obtain as a Schedule 1 substance.

MGC Pharmaceuticals to import psilocybin into Slovenia. It will be exported from Psyence’s production site in South Africa.

The growing market for guided psychedelic experiences. Demand is building for unregulated services.

Optimi Health patents psilocybin extraction method. The company hopes to reduce production costs.

COMPASS to announce Q2 2023 financial results. A corporate update will be released on 3 August.

SCIENCE AND RESEARCH

Exploring the entourage effect in psychedelic mushrooms. Research is needed to understand the synergistic effects of psychoactive compounds.

Comparing psychedelic trips and near-death experiences. Researchers found shared themes, such as ego dissolution.

Ketamine for treatment-resistant depression. Symptoms improved by at least 50 per cent for one-third of patients.

REGULATION AND LEGISLATION

US health officials call for rescheduling of psychedelic medicines. Their Schedule 1 status is a barrier to scientific research.

Veterans advocate for drug decriminalisation in California. Heroic Hearts Project is sponsoring Senate Bill 58.

Amendments to promote psychedelic research cleared for house votes. The measures are attached to a large-scale spending bill.

ARTICLES OF INTEREST

Transatlantic partnership to boost mental health research. The NHS has partnered with New York University.

guide to adaptogens. Adaptogens are increasingly being used therapeutically to manage stress.