Psychedelic profiles: LSD
Lysergic acid diethylamide is a synthetic serotonergic psychedelic. It binds to both serotonin and dopamine receptors, in key contrast to psilocybin, and its effects are noticeable at dosages measured in the millionths of a gram.
In November 1938, Albert Hofmann synthesised LSD-25 for the first time. By 1947, it was introduced as a psychiatric medication under the trade name Delysid by Sandoz and was found to disrupt negative thought patterns.
Although less intensely studied since the turn of the century, LSD has played a pivotal role in psychedelic research and the discovery of serotonin receptors in the brain.EXPLORE OUR PSYCHEDELIC SERIES